Hello lodge308,
To overcome the rebooting issue, simply update your AnywhereUSB driver to the latest (v1.80) following the instructions in Step 2. Before-hand, though, follow instructions in Step 1 for using the AnywhereUSB with an ESX virtual machine.
Step 1 (ESX workaround):
1. Copy the file "usbd.sy_" from the Windows CD that matches your Virtual Machine (the Guest Operating System) to c:\windows(or winnt)\system32\drivers, then rename the file to "usbd.sys".
2. Open the AnywhereUSB Configuration Utility from the start menu, click "View / Driver Information / Uninstall" and reboot that Virtual Machine when prompted.
Step 2 (AnywhereUSB driver update to v1.80):
1. Download the AnywhereUSB driver version 1.80 and save it to your desktop:
http://ftp1.digi.com/support/driver/awusb180.exe
2. Double-click awusb180.exe and continue through the installation. Afterwards, the AnywhereUSB Configuration Utility should launch automatically.
3. Click "Edit / Connection List" and delete all entries. Also delete all entries in "Edit / Discovery List".
4. Disconnect all USB devices from the AnywhereUSB.
5. Immediately after the AnywhereUSB reboots (as soon as it appears on the left-hand side of the Configuration Utility, from the rebooting issue), highlight the AnywhereUSB and then click the "Connect" button. You should get the 1st of 5 found new hardware wizards. Choose "No, not this time" if prompted to connect to Windows Update, then choose "Install the software automatically (Recommended)". Repeat the process for all 5 wizards.
6. Once the AnywhereUSB is installed and ready for use, the five hub port LEDs on the front panel should be solid green. Now plug a USB device into the AnywhereUSB and test it.