There is no artificial limit in the AnywhereUSB hardware or software regarding the maximum number of AnywhereUSBs that can be connected to a single host computer.
CPU speed and memory are the limiting factors.
Hypothetically, it is possible to connect hundreds of AnywhereUSBs to a host computer. The most that Digi has tested is 30 AnywhereUSB/5 units. No issues were observed in this scenario.
Note: You may not have more than 128 USB ports on a single AnywhereUSB device (using USB hubs), due to the USB specifications.
Last updated: Jun 06, 2019